NIGMS

Human Genetic Cell Repository


The NIGMS Human Genetic Cell Repository, sponsored by the National Institute of General Medical Sciences, provides scientists around the world with resources for cell and genetic research. Established in 1972 at the Coriell Institute for Medical Research, the NIGMS Repository contains more than 11,700 cell lines, primarily fibroblasts and transformed lymphoblasts, and more than 5,900 DNA samples. Currently, the NIGMS HGCR catalog also contains over 80 iPSC lines.

Repository samples represent a variety of disease states, chromosomal abnormalities, apparently healthy individuals, and many distinct human populations. These samples comprise over 1,000 different OMIM diagnoses, and have been referenced in over 6,700 scientific publications.

Data on this website and information derived from the samples in the NIGMS Repository may not be used to determine the identity of any individual who provided a sample. Sample data available in the NIGMS Repository regarding race, ethnicity, and/or ancestry is self-reported information provided by sample submitters. Please direct any questions about these policies to NIGMS@coriell.org.

NIGMS News

  • Aug 2021

    Free Cell Line and DNA Samples in Exchange for Molecular Characterization

    The NIGMS Human Genetic Cell Repository is proud to launch a collaborative initiative with the scientific research community in an effort to enhance the molecular and biochemical characterizations of catalog-available samples.

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  • Jun 2021

    NIGMS Repository Teams Up with Cure SURF1 for Urgently Needed Fibroblasts

    The mission was clear. Kasey Woleben needed to collect dozens of skin punches from members of her group, Cure SURF1, and she needed to get fibroblast cells from those samples safely to the University of Texas Southwestern Medical Center. Researchers there had been working on a gene therapy treatment for SURF1 and it was vital to have the cells to prepare an application to the FDA.

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  • May 2021

    NIGMS Repository at the 2021 ISBER Annual Meeting

    The International Society for Biological and Environmental Repositories (ISBER) hosted its annual meeting from May 10-14, 2021 and it was attended by several representatives from the NIGMS Repository and the Coriell Institute’s Repository Leadership Team.

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Other News