Publications

Check out all of our publications on PubMed.

2023

• Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals.
  Richardson, V; Engel, N; Kulathinal, R. Biology of sex differences. 2022. PMID: 37208698

2021

• The role of CTCF in the organization of the centromeric 11p15 imprinted domain interactome.
  Sobel Naveh, NS; Deegan, DF; Huhn, J; Traxler, E; Lan, Y; Wexberg, R; Ganguly, A; Engel, N; Kalish, JM. Nucleic Acids Research. 2021. PMID: 34107024

• Sexual dimorphism of the heart: genetics, epigenetics, and development.
  Deegan, DF.; Nigam, P; Engel, N. Frontiers in Cardiovascular Medicine. 2021. PMID: 34124200

2019

• Sexual Dimorphism in the Age of Genomics: How, When, Where.
  Deegan, Daniel F.; Engel, Nora. Frontiers in cell and developmental biology. 2019. PMID: 31552249

• The developmental origins of sex-biased expression in cardiac development.
  Deegan, Daniel F.; Karbalaei, Reza; Madzo, Jozef; Kulathinal, Rob J.; Engel, Nora. Biology of sex differences. 2019. PMID: 31552249

2018

• Sex Differences in Early Embryogenesis: Inter-Chromosomal Regulation Sets the Stage for Sex-Biased Gene Networks: The dialogue between the sex chromosomes and autosomes imposes sexual identity soon after fertilization.
  Engel, Nora. BioEssays : news and reviews in molecular, cellular and developmental biology. 2018. PMID: 31552249

2017

• A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer.
  Good, Charly R.; Madzo, Jozef; Patel, Bela; Maegawa, Shinji; Engel, Nora; Jelinek, Jaroslav; Issa, Jean-Pierre J. Nucleic acids research. 2017. PMID: 31552249

• Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells.
  Werner, Rachael J.; Schultz, Bryant M.; Huhn, Jacklyn M.; Jelinek, Jaroslav; Madzo, Jozef; Engel, Nora. Biology of sex differences. 2017. PMID: 31552249

2016

• Male-Specific Transcription Factor Occupancy Alone Does Not Account for Differential Methylation at Imprinted Genes in the mouse Germ Cell Lineage.
  Romasko, Edward J.; Engel, Nora. G3 (Bethesda, Md.). 2016. PMID: 31552249

2015

• Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain.
  Schultz, Bryant M.; Gallicio, Gwendolyn A.; Cesaroni, Matteo; Lupey, Lena N.; Engel, Nora. Nucleic acids research. 2015. PMID: 31552249

• Imprinted X chromosome inactivation offers up a double dose of epigenetics.
  Engel, Nora. Proceedings of the National Academy of Sciences of the United States of America. 2015. PMID: 31552249

2012

• The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart.
  Korostowski, Lisa; Sedlak, Natalie; Engel, Nora. PLoS genetics. 2012. PMID: 31552249

• The epigenetic lorax: gene-environment interactions in human health.
  Latham, Keith E.; Sapienza, Carmen; Engel, Nora. Epigenomics. 2012. PMID: 31552249

2011

• Novel cis-regulatory function in ICR-mediated imprinted repression of H19.
  Ideraabdullah, Folami Y.; Abramowitz, Lara K.; Thorvaldsen, Joanne L.; Krapp, Christopher; Wen, Sherry C.; Engel, Nora; Bartolomei, Marisa S. Developmental biology. 2011. PMID: 31552249

• Enhancer-driven chromatin interactions during development promote escape from silencing by a long non-coding RNA.
  Korostowski, Lisa; Raval, Anjali; Breuer, Gillian; Engel, Nora. Epigenetics & chromatin. 2011. PMID: 31552249

2009

• Conserved DNA methylation in Gadd45a(-/-) mice.
  Engel, Nora; Tront, Jennifer S.; Erinle, Toyin; Nguyen, Nghi; Latham, Keith E.; Sapienza, Carmen; Hoffman, Barbara; Liebermann, Dan A. Epigenetics. 2009. PMID: 31552249

2008

• Three-dimensional conformation at the H19/Igf2 locus supports a model of enhancer tracking.
  Engel, Nora; Raval, Anjali K.; Thorvaldsen, Joanne L.; Bartolomei, S. Marisa. Human molecular genetics. 2008. PMID: 31552249

2006

• CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus.
  Engel, Nora; Thorvaldsen, Joanne L.; Bartolomei, Marisa S. Human molecular genetics. 2006. PMID: 31552249

2004

• Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations.
  Engel, Nora; West, Adam G.; Felsenfeld, Gary; Bartolomei, Marisa S. Nature genetics. 2004. PMID: 31552249

• Genomic imprinting: antagonistic mechanisms in the germ line and early embryo.
  Fedoriw, A. M.; Engel, N. I.; Bartolomei, M. S. Cold Spring Harbor symposia on quantitative biology. 2004. PMID: 31552249

2003

• Mechanisms of insulator function in gene regulation and genomic imprinting.
  Engel, Nora; Bartolomei, Marisa S. International review of cytology. 2003. PMID: 31552249