The NIGMS Human Genetic Cell Repository (NIGMS Repository) is sponsored by the National Institute of General Medical Sciences (NIGMS) and supplies scientists with materials for accelerating cell and biomedical research. The resources available include highly characterized, contaminant-free cell cultures and high quality, well-characterized DNA samples derived from these cultures. Established in 1972 at the Coriell Institute for Medical Research, the NIGMS Repository contains more than 11,800 cell lines, primarily fibroblasts and transformed lymphoblasts, and over 5,900 DNA samples. Currently, the NIGMS HGCR catalog also contains over 85 iPSC lines. The NIGMS Repository has a major emphasis on heritable diseases and chromosomally aberrant cell lines. In addition, it contains a large collection dedicated to understanding human variation that includes samples from populations around the world, the CEPH collection, the Polymorphism Discovery Resource, and many apparently healthy controls. Human induced pluripotent stem cell lines, many of which were derived from NIGMS Repository fibroblasts, have recently become available through the NIGMS Repository.
Samples from the collection have been used in more than 6,900 publications and are distributed to scientists in more than 50 countries. This resource is continuously expanding to support new directions in human genetics.
Organization and Contact Information
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NIH Staff Donna Krasnewich, M.D., Ph.D. - Science Officer Ronald Adkins, Ph.D. - Program Officer
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Coriell Staff Nahid Turan, Ph.D. - Principal Investigator Matthew W. Mitchell, Ph.D. - Co-Principal Investigator Jose Santana - Project Lead Eunice Horton - Senior Project Manager La Tonya Willis - Project Manager John Schulz - Project Manager
General Inquiries Email: NIGMS@coriell.org |
