The Coriell Animal and Xenograft Core offers a wide array of services to assist with the design and implementation of xenograft animal studies. The Core maintains a large breeding colony (~30 breeder pairs) of immune-deficient (NSG) mice to meet customer’s demand. Experimental animals are housed in our NSG-dedicated BSL-2 space fully equipped with all the necessary equipment for procedures and survival surgeries.
The facility’s capabilities include a full range of xenograft models, including human CD34+ cells transplanted into NSG mice, orthotopic patient-derived xenograft (PDX) models of hematologic malignancies (AML, ALL), and solid tumor (i.e., hepatic, ovarian, brain, lung) models.
Contacts:
Dr. Zhaorui Lian, Email
Dr. Jian Huang, Email
