Longevity Collection

NIA Aging Cell Repository's Longevity Collection

For studies on successful aging, resources of lymphoblastoid cell lines(LCL) and LCL derived DNA samples from octogenarians, nonagenarians and centenarians are available from the NIA Aging Cell Repository. For each of these collections, the cell lines/DNA were prepared from blood samples that were donated by men and women who have reached great age and whose current health is good, though not necessarily completely healthy. Most donors were interviewed to collect critical information about their age, medical history, family medical history, and demographics. The samples include: 

            Lifetime Study Gerontology Research Center Collection

            This resource includes adult human skin fibroblast cultures from subjects participating in the                                            Baltimore Longitudinal Study of Aging (BLSA). The BLSA was initiated to permit repeated observations of the                  same subjects over a long period of time to quantify true age changes and elucidate mechanisms underlying                  these changes. Observations documented include medical, genetic, biochemical, physiological, and                                  behavioral variables. Information on the donor of any culture is available on request.

            The cultures from these subjects form a unique resource for cellular aging research because of the extensive                database of medical measurements on each donor, the wide range of donor ages (from 17-96), and the                          availability of an in vitro lifespan measurement and karyotype for each culture.

  • Longevity Research Collection 

    Volunteers who had reached the age of 80 or older were sought from elder care facilties in the US for this research project. Subjects were interviewed with respect to medical history and lifestyle before sampling. The data are self-reported although every effort was made to verify their age. The detailed information about Longevity Research collection participants is summarized in a downloadable Excel File. 

  • Sardinian Population of Great Age 

    These individuals are from San Pietro, an island off the southwest coast of Sardinia where many residents attain a great age. 

Custom-made 96-well plates of DNA

Investigators can place custom orders for creation of 96-well plates of the DNA samples of their choosing. Contact NIA Repository principal investigator Deborah Requesens, Ph.D  to request information about custom-plate orders.