NG14285
DNA from Fibroblast
Description:
GERONTOLOGY RESEARCH CENTER (GRC) CELL CULTURE COLLECTION
BALTIMORE LONGITUDINAL STUDY ON AGING (BLSA)
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
GRC |
| Quantity |
10 µg |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Arm
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Cell Type
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Fibroblast
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Tissue Type
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Skin
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Transformant
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Untransformed
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Sample Source
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DNA from Fibroblast
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Race
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White
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Family Member
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3
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Relation to Proband
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brother
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Confirmation
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Clinical summary/Case history
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ISCN
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46,XY
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| PDL at Senescence |
44 |
| PDL at Freeze |
6 |
| Passage Frozen |
3 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis |
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| Remarks |
The biopsy site is the mesial aspect of the mid-upper left arm, taken antemortem. The primary culture was initiated from explants of a 2 mm-punch biopsy. Donor has a history of hypertriglyceridemia and impaired glucose tolerance tests. The cell morphology is fibroblast-like and the karyotype is 46,XY with 6% of the cells examined showing random chromosome loss and 2% showing random chromosomal aberrations. Donor is the brother of AG06282. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
| Kamienieva I, Charzynska A, Duszynski J, Malinska D, Szczepanowska J, In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts Biochimica et biophysica acta Molecular basis of disease1869:166787 2023 |
| PubMed ID: 37302428 |
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