Description:
AGED SIB PAIRS COLLECTION
NIA AGING CELL REPOSITORY DNA PANEL - LONGEVITY COLLECTION
Age:
100 YR
(At Sampling)
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Aged Sib Pairs
Apparently Healthy Collection |
| Quantity |
10ug |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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DNA from LCL
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Race
|
White
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Relation to Proband
|
proband
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Confirmation
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Clinical summary/Case history
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ISCN
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46,XX
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
| |
| Remarks |
The culture was initiated on 4/12/91 by transformation of lymphocytes with Epstein Barr virus. The culture grows in suspension and the cell morphology is spherical. The karyotype is 46,XX with 4% of the cells examined showing random chromosome loss. No aged sibling of this donor is currently available from the Repository. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
| Shokolenko I, Venediktova N, Bochkareva A, Wilson GL, Alexeyev MF, Oxidative stress induces degradation of mitochondrial DNA Nucleic acids research37:2539-48 2009 |
| PubMed ID: 19264794 |
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