NG04151
DNA from Fibroblast
Description:
GERONTOLOGY RESEARCH CENTER (GRC) CELL CULTURE COLLECTION
BALTIMORE LONGITUDINAL STUDY ON AGING (BLSA)
Repository
|
NIA Aging Cell Culture Repository
|
Subcollection |
GRC |
Quantity |
10 µg |
Quantitation Method |
Please see our FAQ |
Biopsy Source
|
Arm
|
Cell Type
|
Fibroblast
|
Tissue Type
|
Skin
|
Transformant
|
Untransformed
|
Sample Source
|
DNA from Fibroblast
|
Race
|
White
|
Family Member
|
1
|
Relation to Proband
|
proband
|
Confirmation
|
Clinical summary/Case history
|
Species
|
Homo sapiens
|
Common Name
|
Human
|
Remarks
|
|
PDL at Freeze |
5.18 |
Passage Frozen |
2 |
|
IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
|
Remarks |
The biopsy site is the mesial aspect of the mid-upper left arm, taken antemortem. The primary culture was initiated from explants of a 2 mm-punch biopsy. The cell morphology is fibroblast-like. The culture is a mosaic with karyotype: 46,XY/46,XY,t(2;18)(2pter>2q33::18q21>18qter;18pter>18q21:: 2q33>2qter); balanced; 60%/40%. A culture initiated from a biopsy taken 16 years later from this same donor is AG13334. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
Behrendt L, Kurth I, Kaether C, A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways Cellular and molecular life sciences : CMLS: 2018 |
PubMed ID: 30666337 |
|
Scaffidi P, Misteli T, Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing Nature cell biology: 2007 |
PubMed ID: 18311132 |
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