| Eriksson I, Wäster P, Öllinger K, Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins Cell death & disease11:370 2019 |
| PubMed ID: 32409651 |
| |
| Lee SW1, Oh YM2, Lu YL3, Kim WK1, Yoo AS4., MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts Developmental Cell46:73-84 2018 |
| PubMed ID: 29974865 |
| |
| Chee YC, Pahnke J, Bunte R, Adsool VA, Madan B, Virshup DM, Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche Developmental cell46:681-695.e5 2017 |
| PubMed ID: 30146480 |
| |
| Dooley A, Gao B, Bradley N, Abraham DJ, Black CM, Jacobs M, Bruckdorfer KR, Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine Rheumatology (Oxford, England)45:676-84 2006 |
| PubMed ID: 16399843 |
| |
| Glaros EN, Kim WS, Quinn CM, Wong J, Gelissen I, Jessup W, Garner B, Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator The Journal of biological chemistry280:24515-23 2005 |
| PubMed ID: 15890646 |
| |
| Kågedal K, Johansson AC, Johansson U, Heimlich G, Roberg K, Wang NS, Jürgensmeier JM, Ollinger K, Lysosomal membrane permeabilization during apoptosis--involvement of Bax? International journal of experimental pathology86:309-21 2005 |
| PubMed ID: 16191103 |
| |
| Stroikin Y, Dalen H, Lööf S, Terman A, Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material European journal of cell biology83:583-90 2005 |
| PubMed ID: 15679103 |
| |
| Tomic-Vatic A, Eytina J, Chapman J, Mahdavian E, Neuzil J, Salvatore BA, Vitamin E amides, a new class of vitamin E analogues with enhanced proapoptotic activity International journal of cancer Journal international du cancer117:188-93 2005 |
| PubMed ID: 15900584 |
| |
| Demoulin JB, Ericsson J, Kallin A, Rorsman C, Ronnstrand L, Heldin CH, Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins. J Biol ChemEpub ahead of print:188-93 2004 |
| PubMed ID: 15213220 |
| |
| Gronroos E, Terentiev AA, Punga T, Ericsson J, YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress. Proc Natl Acad Sci U S AEpub ahead of print:188-93 2004 |
| PubMed ID: 15295102 |
| |
| Stroikin Y, Dalen H, Brunk UT, Terman A, Testing the "garbage" accumulation theory of ageing: mitotic activity protects cells from death induced by inhibition of autophagy Biogerontology6:39-47 2004 |
| PubMed ID: 15834662 |
| |
| Gaus K, Gratton E, Kable EP, Jones AS, Gelissen I, Kritharides L, Jessup W, Visualizing lipid structure and raft domains in living cells with two-photon microscopy. Proc Natl Acad Sci U S A100(26):15554-9 2003 |
| PubMed ID: 14673117 |
| |
| Johansson AC, Steen H, Ollinger K, Roberg K, Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine Cell death and differentiation10:1253-9 2003 |
| PubMed ID: 14576777 |
| |
| Quinn CM, Kågedal K, Terman A, Stroikin U, Brunk UT, Jessup W, Garner B, Induction of fibroblast apolipoprotein E expression during apoptosis, starvation-induced growth arrest and mitosis The Biochemical journal378:753-61 2003 |
| PubMed ID: 14656220 |
| |
| Zhao M, Antunes F, Eaton JW, Brunk UT, Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis European journal of biochemistry / FEBS270:3778-86 2003 |
| PubMed ID: 12950261 |
| |
| Roberg K, Kagedal K, Ollinger K, Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts. Am J Pathol161(1):89-96 2002 |
| PubMed ID: 12107093 |
| |
| Kagedal K, Johansson U, Ollinger K, The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress. FASEB J15(9):1592-4 2001 |
| PubMed ID: 11427496 |
| |
| Baxter BK, Smerdon MJ, Nucleosome unfolding during DNA repair in normal and xeroderma pigmentosum (group C) human cells. J Biol Chem273:17517-24 1998 |
| PubMed ID: 9651343 |
| |
| Berg A, Ekwall AK, Rubin K, Stjernschantz J, Reed RK, Effect of PGE1, PGI2, and PGF2 alpha analogs on collagen gel compaction in vitro and interstitial pressure in vivo. Am J Physiol274:H663-71 1998 |
| PubMed ID: 9486272 |
| |
| Fritz LK, Suquet C, Smerdon MJ, Strand breaks are repaired efficiently in human ribosomal genes. J Biol Chem271:12972-6 1996 |
| PubMed ID: 8662972 |
| |
| Suquet C, Mitchell DL, Smerdon MJ, Repair of UV-induced (6-4) photoproducts in nucleosome core DNA. J Biol Chem270:16507-9 1995 |
| PubMed ID: 7622452 |
| |
| Baenziger NL, Mack P, Jong YJ, Dalemar LR, Perez N, Lindberg C, Wilhelm B, Haddock RC, An environmentally regulated receptor for diamine oxidase modulates human endothelial cell/fibroblast histamine degradative uptake. J Biol Chem269:14892-8 1994 |
| PubMed ID: 8195119 |
| |
| Karlsson C, Paulsson Y, Age related induction of platelet-derived growth factor A-chain mRNA in normal human fibroblasts. J Cell Physiol158:256-62 1994 |
| PubMed ID: 8106562 |
| |
| Saras J, Claesson-Welsh L, Heldin CH, Gonez LJ, Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins. J Biol Chem269:24082-9 1994 |
| PubMed ID: 7929060 |
| |
| Vassbotn FS, Havnen OK, Heldin CH, Holmsen H, Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor. J Biol Chem269:13874-9 1994 |
| PubMed ID: 8188664 |
| |
| Vassbotn FS, Ostman A, Langeland N, Holmsen H, Westermark B, Heldin CH, Nister M, Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line. J Cell Physiol158:381-9 1994 |
| PubMed ID: 8106574 |
| |
| Ben-Ishai R, Scharf R, Sharon R, Kapten I, A human cellular sequence implicated in trk oncogene activation is DNA damage inducible. Proc Natl Acad Sci U S A87:6039-43 1990 |
| PubMed ID: 1696715 |
| |
| DiGiuseppe JA, Hunting DJ, Dresler SL, Aphidicolin-sensitive DNA repair synthesis in human fibroblasts damaged with bleomycin is distinct from UV-induced repair. Carcinogenesis11:1021-6 1990 |
| PubMed ID: 1693320 |
| |
| Ramanathan B, Smerdon MJ, Enhanced DNA repair synthesis in hyperacetylated nucleosomes. J Biol Chem264:11026-34 1989 |
| PubMed ID: 2738057 |
| |
| Dresler SL, Frattini MG, Analysis of butylphenyl-guanine, butylphenyl-deoxyguanosine, and butylphenyl-deoxyguanosine triphosphate inhibition of DNA replication and ultraviolet-induced DNA repair synthesis using permeable human fibroblasts. Biochem Pharmacol37:1033-7 1988 |
| PubMed ID: 3355581 |
| |
| Nagasawa H, Burke MJ, Little FF, McCone EF, Chan GL, Little JB, Multiple abnormalities in the ultraviolet light response of cultured fibroblasts derived from patients with the basal cell nevus syndrome. Teratog Carcinog Mutagen8:25-33 1988 |
| PubMed ID: 2897722 |
| |
| Connolly DT, Stoddard BL, Harakas NK, Feder J, Human fibroblast-derived growth factor is a mitogen and chemoattractant for endothelial cells. Biochem Biophys Res Commun144:705-12 1987 |
| PubMed ID: 3579937 |
| |
| Dresler SL, Kimbro KS, 2',3'-Dideoxythymidine 5'-triphosphate inhibition of DNA replication and ultraviolet-induced DNA repair synthesis in human cells: evidence for involvement of DNA polymerase delta. Biochemistry26:2664-8 1987 |
| PubMed ID: 3606985 |
| |
| Dresler SL, Robinson-Hill RM, Direct inhibition of u.v.-induced DNA excision repair in human cells by novobiocin, coumermycin and nalidixic acid. Carcinogenesis8:813-7 1987 |
| PubMed ID: 3608079 |
| |
| Gale JM, Nissen KA, Smerdon MJ, UV-induced formation of pyrimidine dimers in nucleosome core DNA is strongly modulated with a period of 10.3 bases [published erratum appears in Proc Natl Acad Sci U S A 1989 Nov;86(21):8386] Proc Natl Acad Sci U S A84:6644-8 1987 |
| PubMed ID: 3477794 |
| |
| Cassel D, Katz M, Rotman M, Depletion of cellular ATP inhibits Na+/H+ antiport in cultured human cells. Modulation of the regulatory effect of intracellular protons on the antiporter activity. J Biol Chem261:5460-6 1986 |
| PubMed ID: 3007505 |
| |
| Dresler SL, Frattini MG, DNA replication and UV-induced DNA repair synthesis in human fibroblasts are much less sensitive than DNA polymerase alpha to inhibition by butylphenyl-deoxyguanosine triphosphate. Nucleic Acids Res14:7093-102 1986 |
| PubMed ID: 3763398 |
| |
| Nissen KA, Lan SY, Smerdon MJ, Stability of nucleosome placement in newly repaired regions of DNA. J Biol Chem261:8585-8 1986 |
| PubMed ID: 3722162 |
| |
| Ramanathan B, Smerdon MJ, Changes in nuclear protein acetylation in u.v.-damaged human cells. Carcinogenesis7:1087-94 1986 |
| PubMed ID: 3087643 |
| |
| Smerdon MJ, Completion of excision repair in human cells. Relationship between ligation and nucleosome formation. J Biol Chem261:244-52 1986 |
| PubMed ID: 3941074 |
| |
| Barr FG, Kastan MB, Lieberman MW, Distribution of 5-methyldeoxycytidine in products of staphylococcal nuclease digestion of nuclei and purified DNA. Biochemistry24:1424-8 1985 |
| PubMed ID: 3986183 |
| |
| Dresler SL, Stimulation of deoxyribonucleic acid excision repair in human fibroblasts pretreated with sodium butyrate. Biochemistry24:6861-9 1985 |
| PubMed ID: 4074730 |
| |
| Hunting DJ, Dresler SL, Dependence of u.v.-induced DNA excision repair on deoxyribonucleoside triphosphate concentrations in permeable human fibroblasts: a model for the inhibition of repair by hydroxyurea. Carcinogenesis6:1525-8 1985 |
| PubMed ID: 4042280 |
| |
| Hunting DJ, Dresler SL, de Murcia G, Incorporation of biotin-labeled deoxyuridine triphosphate into DNA during excision repair and electron microscopic visualization of repair patches. Biochemistry24:5729-34 1985 |
| PubMed ID: 3910082 |
| |
| Hunting DJ, Dresler SL, Lieberman MW, Multiple conformational states of repair patches in chromatin during DNA excision repair. Biochemistry24:3219-26 1985 |
| PubMed ID: 3927974 |
| |
| Lan SY, Smerdon MJ, A nonuniform distribution of excision repair synthesis in nucleosome core DNA. Biochemistry24:7771-83 1985 |
| PubMed ID: 4092038 |
| |
| Moore CW, Little JB, Rapid and slow DNA rejoining in nondividing human diploid fibroblasts treated with bleomycin and ionizing radiation. Cancer Res45:1982-6 1985 |
| PubMed ID: 2580615 |
| |
| Moore CW, Malcolm AW, Tomkinson KN, Little JB, Ultrarapid recovery from lethal effects of bleomycin and gamma- radiation in stationary-phase human diploid fibroblasts. Cancer Res45:1978-81 1985 |
| PubMed ID: 2580614 |
| |
| Watkins JF, Smerdon MJ, Nucleosome rearrangement in vitro. 1. Two phases of salt-induced nucleosome migration in nuclei. Biochemistry24:7279-87 1985 |
| PubMed ID: 4084581 |
| |
| Watkins JF, Smerdon MJ, Nucleosome rearrangement in vitro. 2. Formation of nucleosomes in newly repaired regions of DNA. Biochemistry24:7288-95 1985 |
| PubMed ID: 4084582 |
| |
| Weichselbaum RR, Tomkinson K, Little JB, Repair of potentially lethal X-ray damage in fibroblasts derived from patients with hereditary and D-deletion retinoblastoma. Int J Radiat Biol Relat Stud Phys Chem Med47:445-56 1985 |
| PubMed ID: 3872857 |
| |
| Andy RJ, Finstad CL, Old LJ, Lloyd KO, Kornfeld R, The antigen identified by a mouse monoclonal antibody raised against human renal cancer cells is the adenosine deaminase binding protein. J Biol Chem259:12844-9 1984 |
| PubMed ID: 6149219 |
| |
| Andy RJ, Kornfeld R, Biosynthesis of the adenosine deaminase-binding protein in human fibroblasts and hepatoma cells. J Biol Chem259:9832-9 1984 |
| PubMed ID: 6146621 |
| |
| Ben-Ishai R, Sharon R, Rothman M, Miskin R, DNA repair and induction of plasminogen activator in human fetal cells treated with ultraviolet light. Carcinogenesis5:357-62 1984 |
| PubMed ID: 6538462 |
| |
| Cohn SM, Krawisz BR, Dresler SL, Lieberman MW, Induction of replicative DNA synthesis in quiescent human fibroblasts by DNA damaging agents. Proc Natl Acad Sci U S A81:4828-32 1984 |
| PubMed ID: 6589629 |
| |
| Cohn SM, Lieberman MW, The distribution of DNA excision-repair sites in human diploid fibroblasts following ultraviolet irradiation. J Biol Chem259:12463-9 1984 |
| PubMed ID: 6490626 |
| |
| Cohn SM, Lieberman MW, The use of antibodies to 5-bromo-2'-deoxyuridine for the isolation of DNA sequences containing excision-repair sites. J Biol Chem259:12456-62 1984 |
| PubMed ID: 6490625 |
| |
| Dresler SL, Comparative enzymology of ultraviolet-induced DNA repair synthesis and semiconservative DNA replication in permeable diploid human fibroblasts. J Biol Chem259:13947-52 1984 |
| PubMed ID: 6438087 |
| |
| Chan GL, Little JB, Cultured diploid fibroblasts from patients with the nevoid basal cell carcinoma syndrome are hypersensitive to killing by ionizing radiation. Am J Pathol111:50-5 1983 |
| PubMed ID: 6837723 |
| |
| Clarkson JM, Mitchell DL, Adair GM, The use of an immunological probe to measure the kinetics of DNA repair in normal and UV-sensitive mammalian cell lines. Mutat Res112:287-99 1983 |
| PubMed ID: 6633556 |
| |
| Dresler SL, Lieberman MW, Identification of DNA polymerases involved in DNA excision repair in diploid human fibroblasts. J Biol Chem258:9990-4 1983 |
| PubMed ID: 6411709 |
| |
| Dresler SL, Lieberman MW, Requirement of ATP for specific incision of ultraviolet-damaged DNA during excision repair in permeable human fibroblasts. J Biol Chem258:12269-73 1983 |
| PubMed ID: 6630188 |
| |
| Smerdon MJ, Rearrangements of chromatin structure in newly repaired regions of deoxyribonucleic acid in human cells treated with sodium butyrate or hydroxyurea. Biochemistry22:3516-25 1983 |
| PubMed ID: 6615781 |
| |
| Barfknecht TR, Little JB, Abnormal sensitivity of skin fibroblasts from familial polyposis patients to DNA alkylating agents. Cancer Res42:1249-54 1982 |
| PubMed ID: 6800649 |
| |
| Barfknecht TR, Little JB, Survival of hereditary retinoblastoma human skin fibroblasts after treatment with DNA-damaging chemicals. Mutat Res105:189-94 1982 |
| PubMed ID: 6815522 |
| |
| Barfknecht TR, Little JB, Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents. Mutat Res94:369-82 1982 |
| PubMed ID: 6810166 |
| |
| Berger NA, Berger SJ, Catino DM, Abnormal NAD+ levels in cells from patients with Fanconi's anaemia. Nature299:271-3 1982 |
| PubMed ID: 6810184 |
| |
| Dresler SL, Roberts JD, Lieberman MW, Characterization of deoxyribonucleic acid repair synthesis in permeable human fibroblasts. Biochemistry21:2557-64 1982 |
| PubMed ID: 7093202 |
| |
| Kastan MB, Gowans BJ, Lieberman MW, Methylation of deoxycytidine incorporated by excision-repair synthesis of DNA. Cell30:509-16 1982 |
| PubMed ID: 7139710 |
| |
| Smerdon MJ, Lan SY, Calza RE, Reeves R, Sodium butyrate stimulates DNA repair in UV-irradiated normal and xeroderma pigmentosum human fibroblasts. J Biol Chem257:13441-7 1982 |
| PubMed ID: 7142158 |
| |
| Smerdon MJ, Watkins JF, Lieberman MW, Effect of histone H1 removal on the distribution of ultraviolet-induced deoxyribonucleic acid repair synthesis within chromatin. Biochemistry21:3879-85 1982 |
| PubMed ID: 7138811 |
| |
| Chan GL, Little JB, Cross-sensitivity of certain xeroderma pigmentosum and Cockayne syndrome fibroblast strains to both ionizing radiation and ultraviolet light. Mol Gen Genet181:562-3 1981 |
| PubMed ID: 6943407 |
| |
| Cox R, Masson WK, Weichselbaum RR, Nove J, Little JB, The repair of potentially lethal damage in x-irradiated cultures of normal and ataxia telangiectasia human fibroblasts. Int J Radiat Biol Relat Stud Phys Chem Med39:357-65 1981 |
| PubMed ID: 6971846 |
| |
| Nove J, Nichols WW, Weichselbaum RR, Little JB, Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains. Mutat Res84:157-67 1981 |
| PubMed ID: 7329430 |
| |
| Ritter MA, The radiotoxicity of iodine-125 in ataxia telangiectasia fibroblasts. Biochim Biophys Acta652:151-9 1981 |
| PubMed ID: 7213729 |
| |
| Ritter MA, Williams JR, Fluorescent-light-induced lethality and DNA repair in normal and xeroderma pigmentosum fibroblasts. Biochim Biophys Acta655:18-25 1981 |
| PubMed ID: 6266482 |
| |
| Little JB, Nove J, Weichselbaum RR, Abnormal sensitivity of diploid skin fibroblasts from a family with gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C. Mutat Res70:241-50 1980 |
| PubMed ID: 7374661 |
| |
| Malcolm AW, Little JB, Rapid recovery in human diploid fibroblasts. Int J Radiat Biol Relat Stud Phys Chem Med38:439-47 1980 |
| PubMed ID: 6969234 |
| |
| Weichselbaum RR, Little JB, Nove J, Hellman S, Piro AJ, Lack of selective killing by steroids in normal and malignant cells. J Cell Physiol103:429-33 1980 |
| PubMed ID: 7400225 |
| |
| Weichselbaum RR, Nove J, Albert D, Little JB, An in vitro investigation of genetic susceptibility to cancer in diploid fibroblasts from retinoblastoma patients. Teratog Carcinog Mutagen1:171-9 1980 |
| PubMed ID: 6119809 |
| |
| Weichselbaum RR, Nove J, Little JB, X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders. Cancer Res40:920-5 1980 |
| PubMed ID: 7471105 |
| |
| Chan GL, Little JB, Resistance of plateau-phase human normal and xeroderma pigmentosum fibroblasts to the cytotoxic effect of ultraviolet light. Mutat Res63:401-12 1979 |
| PubMed ID: 522880 |
| |
| Nove J, Little JB, Weichselbaum RR, Nichols WW, Hoffman E, Retinoblastoma, chromosome 13, and in vitro cellular radiosensitivity. Cytogenet Cell Genet24:176-84 1979 |
| PubMed ID: 477414 |
| |
| Smerdon MJ, Kastan MB, Lieberman MW, Distribution of repair-incorporated nucleotides and nucleosome rearrangement in the chromatin of normal and xeroderma pigmentosum human fibroblasts. Biochemistry18:3732-9 1979 |
| PubMed ID: 476082 |
| |
| Little, Biological consequences of X-ray induced DNA damage and repair processes in relation to cell killing and carcinogenesis (from DNA Repair Mechanisms, Academic Press, Inc) "DNA Repair Mechanisms"1978, pp 701:3732-9 1978 |
| PubMed ID: 476082 |
| |
| Weichselbaum RR, Nove J, Little JB, X-ray sensitivity of diploid fibroblasts from patients with hereditary or sporadic retinoblastoma. Proc Natl Acad Sci U S A75:3962-4 1978 |
| PubMed ID: 279012 |