Repository NIGMS Human Genetic Cell Repository
Subcollection Apparently Healthy Collection
Class Disorders of the Nervous System
Quantity 10 µg
Quantitation Method Please see our FAQ
Cell Type Fibroblast
Transformant Untransformed
Race Caucasian
Family Member 2
Relation to Proband twin sister
Confirmation Clinical summary/Case history
ISCN 46,XX,t(13;14)(13pter>13q34:: 14q21>14qter;14pter>14q21::13q34>13qter)[15]/46,XX[35]
Species Homo sapiens
Common Name Human
Remarks Line HF25; monozygotic twin of GM04505A; 46,XX/46,XX,t(13;14)(13pter>13q34:: 14q21>14qter;14pter>14q21::13q34>13qter); 66%/30%; 4% of the cells examined show random chromosome loss
Passage Frozen 7
 
Remark Line HF25; monozygotic twin of GM04505A; 46,XX/46,XX,t(13;14)(13pter>13q34:: 14q21>14qter;14pter>14q21::13q34>13qter); 66%/30%; 4% of the cells examined show random chromosome loss
Readhead B, Hartley BJ, Eastwood BJ, Collier DA, Evans D, Farias R, He C, Hoffman G, Sklar P, Dudley JT, Schadt EE, Savic R, Brennand KJ, Expression-based drug screening of neural progenitor cells from individuals with schizophrenia Nature communications9:4412 2018
PubMed ID: 30356048
 
Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH, Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro Cell stem cell22:684-697.e9 2017
PubMed ID: 29727680
 
Seo H, Sonntag KC, Isacson O, Generalized brain and skin proteasome inhibition in Huntington's disease Annals of neurology56:319-28 2004
PubMed ID: 15349858
 
Seo H, Sonntag KC, Isacson O, Generalized brain and skin proteasome inhibition in Huntington's disease Annals of neurology56:319-28 2004
PubMed ID: 29691375
No data is available
Passage Frozen 7
Split Ratio 1:2
Temperature 37 C
Percent CO2 5%
Medium Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids
Serum 15% fetal bovine serum Not inactivated
Substrate None specified
Subcultivation Method trypsin-EDTA