Our Expertise Makes Your Research a Success

research_services

Coriell offers a range of custom research services that have long supported national and international science. Whether you are requesting a cell line for your research studies or submitting DNA samples for genotyping analysis, Coriell is committed to providing you with flexible, innovative, and results-oriented research services. Our laboratories are built to foster scientific collaboration, and your research will benefit from this collaborative environment.

Coriell’s Biobank and Cell Culture Laboratory have established the gold standard in the cryopreservation of biomaterials and the capacity to support varied research worldwide. The diverse collections of biological specimens managed by Coriell offer the scientific community the highest quality specimens, which are necessary for successful research endeavors. Since the first repository – a National Institutes of Health collection – was established at Coriell in 1964, millions of cell lines and DNA samples have been distributed to researchers in 66 countries; more than 7,000 peer-reviewed papers have been published citing over 12,000 biospecimens from the Coriell Biobank.

The service offerings through the Coriell Cytogenetics Laboratory combine conventional and molecular cytogenetic analyses, such as G-banded karyotyping and FISH analysis, with modern cytogenomic technologies capable of capturing chromosome rearrangements at a very high resolution. This genomic service is performed in Coriell’s Genotyping and Microarray Center – one of the nation’s highest-throughput facilities, with systems from Affymetrix and Illumina, and CLIA certification and licensure. If your samples require DNA or RNA isolation before genotyping, Coriell’s Molecular Biology Laboratory can perform this service. Coriell also offers research study design and expertise to support data interpretation and other study requirements.

The Coriell Stem Cell Biobank (SCB) is committed to providing scientists with the opportunity to bank their pluripotent stem cell lines, while also developing in-house human induced pluripotent stem (iPS) cell lines for distribution for researchers. The services offered by the SCB include characterization of iPS cell lines and mouse embryonic stem cell (mESC) lines, such as embryoid body formation, germ-layer specific gene expression, surface antigen testing, and in vitro differentiation.

All services are performed under strict quality systems and to the ISO 9001:2008 standard. Throughout the history of the Coriell Institute for Medical Research, the Institute has sought to achieve the highest standards of performance and safety. To this end, the Institute has an Emergency Operations Plans, Exposure Control Policy, and Laboratory Safety Plan. In addition, each department has its own quality control (QC) and quality assurance (QA) procedures. As an experienced manager of biobanks, Coriell has in-place systems for detecting and resolving any emerging problems associated with QC. 

When you work with Coriell, you are partnering with an institute that prides itself on providing researchers the best in technology and practices. Choose from our research services below; each page offers an overview of our service, contact information, protocols and instructions, and educational materials.

We look forward to working with you.

Biobanking

Biobanking

Key services include banking, cryopreservation, and fail-safe storage of cell lines, DNA, and other biomaterials; online catalog of annotated samples. [ Learn More ]

Biomarkers

Biomarkers

Key services include receipt and storage of a variety of samples at optimal temperature, processing of samples to yield DNA and RNA, and reporting of life-cycle of samples [ Learn More ]


Cell Culture

Cell Culture

Key services include establishment of cell lines, preparation of buffy coats (peripheral blood mononuclear cells), growth of cell lines for isolation of nucleic acids and proteins, EBV-transformation of lymphocytes, primary fibroblasts, and differentiated cell lines from biopsy. [ Learn More ]

Cytogenetics

Cytogenetics

Key services include karyotype analysis, FISH analysis, and cytogenetic techniques including copy number variation and loss of heterozygosity. [ Learn More ]


Genotyping & Microarray

Genotyping & Microarray

Key services include Affymetrix platform expression profiling, genome-wide genotyping, copy number variation analysis, and Illumina BeadXpress platform. [ Learn More ]

Molecular Biology

Molecular Biology

Key services include DNA and RNA isolation, whole genome amplification (WGA), and Mycoplasma testing. [ Learn More ]


Quality at Coriell

Quality at Coriell

Coriell upholds rigorous standards for performance and safety. All services are conducted under strict quality systems.  [ Learn More ]

Research Design & Expertise

Research Design & Expertise

Key services include protocol and research design, data interpretation, and research support. [ Learn More ]


Stem Cells

Stem Cells

Key services include cell characterization, karotype and microsatellite analyses, and sterility testing. [ Learn More ]