Description:
MULTIPLE CELL LINES FROM SAME SUBJECT - EBV TRANSFORMED B LYMPHOCYTE
APPARENTLY HEALTHY INDIVIDUAL
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Apparently Healthy Collection |
| Quantity |
25 µg |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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DNA from LCL
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Race
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White
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Country of Origin
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USA
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Family Member
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1
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Family History
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N
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin confirmed by LINE assay |
| |
| Remarks |
Clinically normal; other lymphoblast cell cultures from this same individual are GM22648, GM22649, GM22650 and GM22651 |
| Lecca M, Bedeschi MF, Izzi C, Dordoni C, Rinaldi B, Peluso F, Caraffi SG, Prefumo F, Signorelli M, Zanzucchi M, Bione S, Ghigna C, Sassi S, Novelli A, Valente EM, Superti-Furga A, Garavelli L, Errichiello E, Identification of bi-allelic LFNG variants in three patients and further clinical and molecular refinement of spondylocostal dysostosis 3 Clinical genetics: 2023 |
| PubMed ID: 37038048 |
| |
| Laczik M, Erdos E, Ozgyin L, Hevessy Z, Csosz É, Kalló G, Nagy T, Barta E, Póliska S, Szatmári I, Bálint BL, Extensive proteome and functional genomic profiling of variability between genetically identical human B-lymphoblastoid cells Scientific data9:763 2022 |
| PubMed ID: 36496436 |
| |
| Rodden LN, Gilliam KM, Lam C, Rojsajjakul T, Mesaros C, Dionisi C, Pook M, Pandolfo M, Lynch DR, Blair IA, Bidichandani SI, DNA methylation in Friedreich ataxia silences expression of frataxin isoform E Scientific reports12:5031 2021 |
| PubMed ID: 35322126 |
| |
| Rodden LN, Chutake YK, Gilliam K, Lam C, Soragni E, Hauser L, Gilliam M, Wiley G, Anderson MP, Gottesfeld JM, Lynch DR, Bidichandani SI, Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia Human molecular genetics29:3818-3829 2020 |
| PubMed ID: 33432325 |
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| Arumugam K, Shin W, Schiavone V, Vlahos L, Tu X, Carnevali D, Kesner J, Paull EO, Romo N, Subramaniam P, Worley J, Tan X, Califano A, Cosma MP, The Master Regulator Protein BAZ2B Can Reprogram Human Hematopoietic Lineage-Committed Progenitors into a Multipotent State Cell reports33:108474 2019 |
| PubMed ID: 33296649 |
| |
| Ozgyin L, Horvath A, Hevessy Z, Balint BL, Extensive epigenetic and transcriptomic variability between genetically identical human B-lymphoblastoid cells with implications in pharmacogenomics research Scientific reports9:4889 2018 |
| PubMed ID: 30894562 |
| |
| Scheinfeldt LB1, Hodges K2, Pevsner J3, Berlin D2, Turan N2, Gerry NP2,4., Genetic and genomic stability across lymphoblastoid cell line expansions BMC Research Notes11:4889 2018 |
| PubMed ID: 30075799 |
| |
| Barbara Canonico, Erica Cesarini, Sara Salucci, Francesca Luchetti, Elisabetta Falcieri, Gianna Di Sario, Fulvio Palma, and Stefano Papa1., Defective Autophagy, Mitochondrial Clearance and Lipophagy in Niemann-Pick Type B Lymphocytes. Plos One11(10):e0165780 2016 |
| PubMed ID: 27798705 |
| |
| Shirley MD, Baugher JD, Stevens EL, Tang Z, Gerry N, Beiswanger CM, Berlin DS, Pevsner J, Chromosomal variation in lymphoblastoid cell lines Human mutation33:1075-86 2011 |
| PubMed ID: 22374857 |
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