NA03320
DNA from Fibroblast
Description:
NEUROBLASTOMA; NB NEUROBLASTOMA SUPPRESSOR, INCLUDED; NBS, INCLUDED
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Heritable Diseases |
| Class |
Disorders of the Nervous System |
| Quantity |
10 µg |
| Quantitation Method |
Please see our FAQ |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Sample Source
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DNA from Fibroblast
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
55 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
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| Remarks |
IMR-32; ATCC CCL 127; fibroblast and neuroblast-like cell culture; G6PD type B; hyperdiploid; short arm of chromosome #1 shows an HSR |
| Carlock L, Wisniewski D, Lorincz M, Pandrangi A, Vo T, An estimate of the number of genes in the Huntington disease gene region and the identification of 13 transcripts in the 4p16.3 segment. Genomics13:1108-18 1992 |
| PubMed ID: 1387107 |
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| Gaskin F, Kingsley BS, Fu SM, Autoantibodies to neurofibrillary tangles and brain tissue in Alzheimer's disease. Establishment of Epstein-Barr virus-transformed antibody-producing cell lines [published erratum appears in J Exp Med 1987 Mar 1;165(3):937] J Exp Med165:245-50 1987 |
| PubMed ID: 3025332 |
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| Kohl NE, Legouy E, DePinho RA, Nisen PD, Smith RK, Gee CE, Alt FW, Human N-myc is closely related in organization and nucleotide sequence to c-myc. Nature319:73-7 1986 |
| PubMed ID: 3510398 |
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| Yura Y, Terashima K, Iga H, Yanagawa T, Yoshida H, Hayashi Y, Sato M, A latent infection of herpes simplex virus type 2 in a human neuroblastoma cell line IMR-32. Arch Virol90:249-60 1986 |
| PubMed ID: 3015082 |
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| Shiloh Y, Shipley J, Brodeur GM, Bruns G, Korf B, Donlon T, Schreck RR, Seeger R, Sakai K, Latt SA, Differential amplification, assembly, and relocation of multiple DNA sequences in human neuroblastomas and neuroblastoma cell lines. Proc Natl Acad Sci U S A82:3761-5 1985 |
| PubMed ID: 3858848 |
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| Schwab M, Ellison J, Busch M, Rosenau W, Varmus HE, Bishop JM, Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma. Proc Natl Acad Sci U S A81:4940-4 1984 |
| PubMed ID: 6589638 |
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| Halton DM, Peterson WD Jr, Hukku B, Cell culture quality control by rapid isoenzymatic characterization. In Vitro19:16-24 1983 |
| PubMed ID: 6401685 |
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| Bhattacharya P, Basu S, Probable involvement of a glycoconjugate in IMR-32 DNA synthesis: decrease of DNA polymerase alpha 2 activity after tunicamycin treatment. Proc Natl Acad Sci U S A79:1488-91 1982 |
| PubMed ID: 6951191 |
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| Bhattacharya P, Simet I, Basu S, Differential inhibition of multiple forms of DNA polymerase alpha from IMR-32 human neuroblastoma cells. Proc Natl Acad Sci U S A78:2683-7 1981 |
| PubMed ID: 6942402 |
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| Rousset M, Zweibaum A, Fogh J, Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins. Cancer Res41:1165-70 1981 |
| PubMed ID: 7459858 |
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| Seeger RC, Rosenblatt HM, Imai K, Ferrone S, Common antigenic determinants on human melanoma, glioma, neuroblastoma, and sarcoma cells defined with monoclonal antibodies. Cancer Res41:2714-7 1981 |
| PubMed ID: 6166367 |
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| Wright WC, Daniels WP, Fogh J, Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis. J Natl Cancer Inst66:239-47 1981 |
| PubMed ID: 6935474 |
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| Balaban-Malenbaum, The proposed origin of double minutes from homogeneously staining region (HSR) - marker chromosomes in human neuroblastoma hybrid cell lines. Cancer Genet Cytogenet2:339 (1980):239-47 1980 |
| PubMed ID: 6935474 |
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| Momoi M, Kennett RH, Glick MC, A membrane glycoprotein from human neuroblastoma cells isolated with the use of a monoclonal antibody. J Biol Chem255:11914-21 1980 |
| PubMed ID: 6160155 |
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| Balaban-Malenbaum G, Gilbert F, Double minute chromosomes and the homogeneously staining regions in chromosomes of a human neuroblastoma cell line. Science198:739-41 1977 |
| PubMed ID: 71759 |
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| Fogh J, Fogh JM, Orfeo T, One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst59:221-226 1977 |
| PubMed ID: 327080 |
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| Fogh J, Wright WC, Loveless JD, Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J Natl Cancer Inst58:209-214 1977 |
| PubMed ID: 833871 |
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| Biedler JL, Spengler BA, Metaphase chromosome anomaly: association with drug resistance and cell- specific products. Science191:185-7 1976 |
| PubMed ID: 942798 |
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| Tumilowicz JJ, Nichols WW, Cholon JJ, Greene AE, Definition of a continuous human cell line derived from neuroblastoma. Cancer Res30:2110-8 1970 |
| PubMed ID: 5459762 |
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