| Remarks |
Clinically affected; symptom onset at age 38 years; diagnosis at age 39 years;
numbness in arms and hands; loss of dexterity; mild hammertoes; high arched feet; wide, unsteady steppage gait; down going toes bilaterally; mild foot drop; tripping, especially with right foot; decreased pinprick sensation below the knees bilaterally; absent vibratory sensation in the toes bilaterally; decreased temperature sensation in the legs distally; mild weakness of foot dorsiflexion bilaterally; subject also has a history of: degenerative spinal cord compression; carpal tunnel syndrome; hyperthyroidism; depression and psoriatic arthritis; CMT diagnosed by nerve conduction velocity studies conducted at MDA clinic: evidence of sensorimotor polyneuropathy with predominantly demyelinating features and secondary axonal changes consistent with CMT; MRI of spine revealed evidence of myelomalacia at the C5-6 level; C6 cord compression; assistive devices include hand splints for carpel tunnel (worn inconsistently); surgeries include carpal tunnel release, shunt, cervical fusion, cervical laminectomy, lumbar drain, anterior cervical tissue graft; medications include Plaquenil, Methotrexate Sodium, Hydrocodone, Aleve/Excedrin, Flexeril, Sulfasalazine, Levothyroid, and Enbrel; father and sibling are also reported to be affected with CMT.
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