Description:
MAJOR AFFECTIVE DISORDER - 125480 OR 309200
Repository
|
NIGMS Human Genetic Cell Repository
|
Subcollection |
Heritable Diseases |
Class |
Disorders of the Nervous System |
Cell Type
|
Fibroblast
|
Transformant
|
Untransformed
|
Race
|
White
|
Ethnicity
|
JEWISH
|
Family Member
|
7
|
Relation to Proband
|
maternal cousin
|
Confirmation
|
Clinical summary/Case history
|
Species
|
Homo sapiens
|
Common Name
|
Human
|
Remarks
|
|
Passage Frozen |
6 |
|
IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
|
Remarks |
Cyclothymic personality; minor depression; onset at age 14; see GM07200B Lymphoid; maternal 1st cousin of a bipolar male |
Gershon ES, Targum SD, Matthysse S, Bunney WE Jr, Color blindness not closely linked to bipolar illness. Report of a new pedigree series. Arch Gen Psychiatry36:1423-30 1979 |
PubMed ID: 316315 |
Passage Frozen |
6 |
Split Ratio |
1:3 |
Temperature |
37 C |
Percent CO2 |
5% |
Medium |
Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent |
Serum |
15% fetal bovine serum Not inactivated |
Substrate |
None specified |
Subcultivation Method |
trypsin-EDTA |
Supplement |
- |
|
|