AG05251
Fibroblast from Skin, Arm
Description:
GORILLA GORILLA
ORDER: PRIMATES
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Nonhuman Primates
Animals |
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Biopsy Source
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Arm
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Cell Type
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Fibroblast
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Tissue Type
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Skin
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Transformant
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Untransformed
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Sample Source
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Fibroblast from Skin, Arm
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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48,XX,ps+
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Species
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Gorilla gorilla
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Common Name
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gorilla
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Remarks
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| PDL at Freeze |
17 |
| Passage Frozen |
11 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis |
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| Genbank |
Apolipoprotein B |
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| Genbank |
Plasminogen |
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| Genbank |
Lipoprotein Lp(a) |
| Choby JE, Buechi HB, Farrand AJ, Skaar EP, Barber MF, Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus mBio9: 2018 |
| PubMed ID: 30459189 |
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| Babcock M, Yatsenko S, Stankiewicz P, Lupski JR, Morrow BE, AT-rich repeats associated with chromosome 22q112 rearrangement disorders shape human genome architecture on Yq12 Genome research17:451-60 2007 |
| PubMed ID: 17284672 |
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| Han K, Sen SK, Wang J, Callinan PA, Lee J, Cordaux R, Liang P, Batzer MA, Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages. Nucleic Acids Res33(13):4040-52 2005 |
| PubMed ID: 16034026 |
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| Ho HJ, Ray DA, Salem AH, Myers JS, Batzer MA, Straightening out the LINEs: LINE-1 orthologous loci. Genomics85(2):201-7 2005 |
| PubMed ID: 15676278 |
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| Inagaki H, Ohye T, Kogo H, Yamada K, Kowa H, Shaikh TH, Emanuel BS, Kurahashi H, Palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved in primates Human mutation26:332-42 2005 |
| PubMed ID: 16116616 |
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| Rowen L, Williams E, Glusman G, Linardopoulou E, Friedman C, Ahearn ME, Seto J, Boysen C, Qin S, Wang K, Kaur A, Bloom S, Hood L, Trask BJ, Interchromosomal segmental duplications explain the unusual structure of PRSS3, the gene for an inhibitor-resistant trypsinogen Molecular biology and evolution22:1712-20 2005 |
| PubMed ID: 15901841 |
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| Salem AH, Ray DA, Hedges DJ, Jurka J, Batzer MA, Analysis of the human Alu Ye lineage. BMC Evol Biol5(1):18 2005 |
| PubMed ID: 15725352 |
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| Song B, Gold B, O'Huigin C, Javanbakht H, Li X, Stremlau M, Winkler C, Dean M, Sodroski J, The B302(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates Journal of virology79:6111-21 2005 |
| PubMed ID: 15857996 |
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| Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM, Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol2(7):E207 2004 |
| PubMed ID: 15252450 |
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| Hahn MW, Rockman MV, Soranzo N, Goldstein DB, Wray GA, Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. Genetics167(2):867-77 2004 |
| PubMed ID: 15238535 |
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| Otieno AC, Carter AB, Hedges DJ, Walker JA, Ray DA, Garber RK, Anders BA, Stoilova N, Laborde ME, Fowlkes JD, Huang CH, Perodeau B, Batzer MA, Analysis of the human Alu Ya-lineage. J Mol Biol342(1):109-18 2004 |
| PubMed ID: 15313610 |
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| Ejima Y, Yang L, Trans mobilization of genomic DNA as a mechanism for retrotransposon-mediated
exon shuffling. Hum Mol Genet12(11):1321-8 2003 |
| PubMed ID: 12761047 |
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| Johanning K, Stevenson CA, Oyeniran OO, Gozal YM, Roy-Engel AM, Jurka J, Deininger PL, Potential for retroposition by old Alu subfamilies Journal of molecular evolution56:658-64 2003 |
| PubMed ID: 12911029 |
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| Salem AH, Kilroy GE, Watkins WS, Jorde LB, Batzer MA, Recently integrated Alu elements and human genomic diversity. Mol Biol Evol20(8):1349-61 2003 |
| PubMed ID: 12777511 |
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| Zhang J, Webb DM, Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates. Proc Natl Acad Sci U S A100(14):8337-41 2003 |
| PubMed ID: 12826614 |
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| Myers JS, Vincent BJ, Udall H, Watkins WS, Morrish TA, Kilroy GE, Swergold GD, Henke J, Henke L, Moran JV, Jorde LB, Batzer MA, A comprehensive analysis of recently integrated human Ta L1 elements. Am J Hum Genet71(2):312-26 2002 |
| PubMed ID: 12070800 |
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| Shaikh TH, Kurahashi H, Emanuel BS, Evolutionarily conserved low copy repeats (LCRs) in 22q11 mediate deletions, duplications, translocations, and genomic instability: an update and literature review. Genet Med3(1):6-13 2001 |
| PubMed ID: 11339380 |
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| Samonte RV,Conte RA,Verma R, Localization of human midisatellite and macrosatellite DNA sequences on chromosomes 1 and X in the great apes. J Hum Genet44:57-9 1999 |
| PubMed ID: 9929980 |
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| Barrientos A, Kenyon L, Moraes CT, Human xenomitochondrial cybrids. Cellular models of mitochondrial complex I deficiency. J Biol Chem273(23):14210-7 1998 |
| PubMed ID: 9603924 |
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| Conte RA,Samonte RV,Verma R, Evolutionary divergence of the oncogenes GLI, HST and INT2. Heredity81 ( Pt 1):10-3 1998 |
| PubMed ID: 9720300 |
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| Tarazami ST,Kringstein AM,Conte RA,Verma R, Comparative mapping of the cri du chat and DiGeorge syndrome regions in the great apes. Genes Genet Syst73:135-6 1998 |
| PubMed ID: 9718678 |
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| Kenyon L,Moraes C, Expanding the functional human mitochondrial DNA database by the establishment of primate xenomitochondrial cybrids. Proc Natl Acad Sci U S A94:9131-5 1997 |
| PubMed ID: 9256447 |
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| Samonte RV,Conte RA,Verma R, Brief communication: comparative mapping of the human estrogen receptor (ESR) and the Kallmann (KAL) regions to the chromosomes of the great apes. Am J Phys Anthropol103:561-3 1997 |
| PubMed ID: 9292171 |
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| Samonte RV,Ramesh KH,Verma R, Comparative mapping of human alphoid satellite DNA repeat sequences in the great apes. Genetica101:97-104 1997 |
| PubMed ID: 9465402 |
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| Tarzami ST,Kringstein AM,Conte RA,Verma R, Unique genomic sequences in human chromosome 16p are conserved in the great apes. Mol Gen Genet253:512-4 1997 |
| PubMed ID: 9037113 |
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| Samonte RV,Conte RA,Verma R, Conservation of p58 and c-myc protooncogene sequences in the great apes. Chromosome Res4:321-2 1996 |
| PubMed ID: 8817075 |
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| Samonte RV,Ramesh KH,Verma R, Regional localization of human M-BCR gene to chromosome 23 band q11 in the great apes. Genetica98:111-3 1996 |
| PubMed ID: 8765683 |
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| Tarzami ST,Kringstein AM,Conte RA,Verma R, A unique genomic sequence in the Wolf-Hirschhorn syndrome [WHS] region of humans is conserved in the great apes. Genetica98:217-9 1996 |
| PubMed ID: 8976066 |
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| Chang DY, Sasaki-Tozawa N, Green LK, Maraia RJ, A trinucleotide repeat-associated increase in the level of Alu RNA- binding protein occurred during the same period as the major Alu amplification that accompanied anthropoid evolution. Mol Cell Biol15:2109-16 1995 |
| PubMed ID: 7534378 |
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| Ermert K,Mitlohner H,Schempp W,Zachau H, The immunoglobulin kappa locus of primates. Genomics25:623-9 1995 |
| PubMed ID: 7759095 |
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| Greco RM, Ehrlich HP, Differences in cell division and thymidine incorporation with rat and primate fibroblasts in collagen lattices. Tissue Cell24:843-51 1992 |
| PubMed ID: 1485326 |
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| Schempp W, Weber B, Muller G, Mammalian sex-chromosome evolution: a conserved homoeologous segment on the X and Y chromosomes in primates. Cytogenet Cell Genet50:201-5 1989 |
| PubMed ID: 2805817 |
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| Weber B, Weissenbach J, Schempp W, Conservation of human-derived pseudoautosomal sequences on the sex chromosomes of the great apes. Cytogenet Cell Genet45(1):26-9 1987 |
| PubMed ID: 3474106 |
| Cumulative PDL at Freeze |
17 |
| Passage Frozen |
11 |
| Split Ratio |
1:4 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Percent O2 |
AMBIENT |
| Medium |
MEM (Eagle) Alpha Modification with nucleosides/Dulbecco Modified Eagles Medium (high glucose), 1:1 mixture with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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