Cytogenomics

The Cytogenomics Laboratory at Coriell is a state-of-the-art facility performing conventional G-banded karyotype and molecular cytogenetic analysis on various human cell types including fibroblast, lymphoblast, and stem cells.  The laboratory is equipped with a network of CytoVision™ Image Analysis and Capturing Systems,  that work in conjunction with GSL automated slide loader, and CytoVision software to automate image capture and enhance the quality of G-band analysis.

Detailed analysis of genome-wide unbalanced chromosomal aberrations, such as copy number variations (CNVs) and loss of heterozygosity (LOH) or long contiguous stretches of homozygosity (LCSHs), are performed using the Affymetrix Genome-Wide Human SNP Array 6.0.

Cytogenomic analysis is interpreted and signed-out by a board-certified Cytogeneticist.

Key Cytogenomic Services at Coriell

  • G-banded karyotype analysis
  • Affymetrix Genome-Wide Human SNP Array 6.0
  • Cytogenomic services for quality control in stem cell research

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The Coriell Institute for Medical Research’s quality management system has been certified to the ISO 9001:2015 standard.