Why Coriell?


Pioneering Legacy

Innovation that forever changed the landscape of science and medicine is the legacy of our founder and namesake, Dr. Lewis Coriell. Dr. Coriell developed aseptic cell culture techniques and played a critical role in the discovery of the polio vaccine. Today, scientists at Coriell are proud to continue in his innovative footsteps by defining best practices in biobanking, producing and distributing high quality biomaterials, offering exceptional laboratory services and leading the charge in personalized medicine.

Trusted Partner

Coriell sets the international gold standard in biobanking and laboratory services and is the trusted steward of world-renowned collections for the National Institutes of Health, disease foundations and commercial clients. Coriell stores and distributes some of the most diverse collections of biospecimens of diseased and healthy human populations in the world. Through the Coriell Personalized Medicine Collaborative, a groundbreaking study of precision medicine, Coriell is collaborating with the Department of Defense to study the genetic data of United States Air Force members.

Superior Quality

As an ISO9001:2008 certified institute, Coriell seeks to achieve the highest standards of performance and safety across all operations. Coriell follows rigorous protocols for sample collection, processing, storage and distribution
and offers an unparalleled IT infrastructure to provide custom solutions for key business and scientific programs. Our commitment to quality sets the standard for biobanks around the globe.


Biobanking

  • Public, private and independent biobanks
  • Cryopreservation (-20°C, -80°C, Liquid Nitrogen – vapor, Liquid Nitrogen)
  • Repository Information Management Systems
  • Online catalog with extensive annotation
  • Controlled-access to samples and associated data

Research Support Services

  • Data analysis
  • Quality assurance certification
  • Customized project reports
  • Advice on human subject research and Institutional Review Board approval

Cell Culture

  • Establishment of cell lines from tissue and blood
  • Isolation and cryopreservation of buffy coats (peripheral blood mononuclear cells)
  • Expansion of cell lines for replenishment, distribution, and molecular and cytogenetic analysis
  • Sterility and viability assessment of existing cell lines

Collection Kits

  • Skin biopsy collection kits
  • Biomarker kits
  • Blood collection kits: adult and pediatric
  • Saliva collection kits: DNA and RNA extraction

Molecular Biology

  • DNA and RNA isolation
  • Customized plates and panels
  • Identity, species, gender and family pedigree testing and verification

Biomarkers

  • Receipt and storage of a variety of biosamples
  • Processing of biospecimens to yield DNA and RNA
  • Reporting of life-cycle of samples; enterprise level LIMS
  • Hemoglobin assays to assess quality of serum, plasma, andcerebrospinal fluid
  • Development of additional biomarker assays and quality control

Sequencing and Genotyping

  • Affymetrix Genome-Wide Human SNP Array 6.0*
  • Affymetrix DMET Plus*
  • Genotyping (Taqman assay)
  • Copy number variation (CYP2D6 Copy number assay*)
  • Next Generation Sequencing

Cytogenomics

  • G-banded karyotype analysis
  • Affymetrix Genome-Wide Human SNP Array 6.0
  • Cytogenomic services for quality control in stem cell research

Stem Cells

  • Post-thaw viability and growth rate testing
  • Sterility assessment
  • Alkaline phosphatase staining
  • Karyotyping to identify chromosomal abnormalities
  • Assessment of differentiation potential
  • Pluripotency assay

Cell Line Integrity

  • Mycoplasma Testing
  • Cell Line Authentication/DNA Fingerprinting
  • Cytogenomics


(*clinical molecular diagnostic CLIA-approved service)